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mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
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mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
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mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
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mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
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mRNA expression of TLR8 (A), <t>TLR7</t> (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.
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mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.

Journal: Journal of leukocyte biology

Article Title: TLR8 Ligation Induces Apoptosis of Monocytic Myeloid-Derived Suppressor Cells

doi: 10.1002/JLB.5AB0217-070R

Figure Lengend Snippet: mRNA expression of TLR8 (A), TLR7 (B) and TLR9 (C) on mDC, pDC, mMDSC and gMDSC in three donors. Columns and bars represents mean (± SE) of duplicate measurements. mMDSC, white column; other cell types, black columns.

Article Snippet: In some assays, the cells were cultured with 0.5uM and 2uM of TLR7/8 agonist CL-075, 10uM and 50uM of TLR7 agonist Imiquimod, and 50nM and 100nM of TLR 9 agonist CpG ODN2006 with PBS control (all InvivoGen).

Techniques: Expressing